Human evidence can mean a controlled clinical study, an observational study, a safety or exposure report, or evidence from a particular finished formulation. Those are different kinds of information.
Mostly laboratory or animal evidence. The evidence is mainly from cells, tissues, or animals. Any human information is limited or indirect and does not establish a clinical outcome.
The systematic review found that the evidence base was dominated by animal studies, with very limited human data and no basis for routine clinical conclusions.
- Evidence type
- Preclinical evidence
Limits and source
Human effectiveness, long-term safety, pharmacokinetics, manufacturing consistency, and the relevance of animal findings are unresolved. Lack of robust human trials is an absence of evidence, not proof of no biological activity.
Open source [1]How to interpret the evidence label
More human evidence does not automatically mean better results for a different product, route, population, or purpose. Limited or missing evidence does not prove that a compound has no biological activity; it means the relevant clinical question has not been established by the published material reviewed here.
